Before becoming a Senator, Javits fought in World War 2 and served in the House of Representatives. In 1954, he defeated Franklin Delano Roosevelt Jr. to become the Attorney General of New York. As Senator, Javits played a significant role in the passage of the 1964 civil rights act.

During his time in the Clinton administration, Robert Rubin served as director of the National Economic Council and played a crucial role in the passing of NAFTA. Aside from government, Rubin also served on the board of directors at Citigroup, and as co-chairman of Goldman-Sachs.

Emanuel is a member of the Democratic Party. He previously served as the 55th Mayor of Chicago from 2011 to 2019, the 23rd White House Chief of Staff from 2009 to 2010, and as a member of the US House of Representatives representing Illinois from 2003 to 2009.

Manning is a member of the Democratic Party.

She had previously ran for election in North Carolina's 13th Congressional District in 2018.

Jacobs is a member of the Democratic Party.

Her grandfather, Irwin M. Jacobs, founded the international technology corporation Qualcomm.

Auchincloss is a member of the Democratic Party.

He is also a businessman and a veteran of the US Marine Corps.

Bonamici is a member of the Democratic Party.

According to the Jewish Virtual Library, she was raised Episcopalian and Unitarian, but now practices Judaism with her Jewish husband, Michael Simon.

Ossoff is a member of the Democratic Party. He previously worked as a documentary film producer and investigative journalist.

Shulsky has also worked for RAND Corporation, an American nonprofit global policy think tank that receives funding from the US government, and The Hudson Institute, a Washington DC-based conservative think tank.

Polis, who is openly gay, has made history several times through his electoral success. He became the first same-sex parent elected to the US Congress in 2008, the first openly gay man elected governor of a U.S. state in 2018, and the first Jewish governor of Colorado. In 2020, he became the first U.S. governor to be engaged to a same-sex partner.

As the first husband of a vice president in American history, Emhoff is the first person to ever hold the title "second gentleman". He is also the first Jewish spouse of a vice president.

President Biden has claimed Hallie's mother, Joan Olivere, was his childhood crush.

Biden's other children also married Jews; Hunter Biden married Melissa Cohen, and Ashley Biden married Howard Krein.

Cohen is the wife of Hunter Biden, one of President Joe Biden's sons.

Biden's other children also married Jews; Beau Biden married Hallie Olivere, and Ashley Biden married Howard Krein.

Abrams is perhaps best known for his involvement with the Iran Contra Affair, which led to his conviction in 1991 on two misdemeanor counts of unlawfully withholding information from Congress. He was later pardoned by President George H. W. Bush.

Kristol was an avid "Never Trumper" Republican associated with numerous conservative think tanks, such as the Project for the New American Century (which he co-founded with Robert Kagan).

Perle has been involved with numerous political think-tanks, such as the Washington Institute for Near East Policy, the Jewish Institute for National Security of America (JINSA), and the Project for the New American Century, which was co-founded by Bill Kristol and Robert Kagan.

The ‘Bush Doctrine’ is purported to have used elements of the 1992 ‘Wolfowitz Doctorine’ for international goals, including pre-emptive foreign intervention and democratic regime change. Wolfowitz, as Deputy Secretary of Defense, was at the center of the administration's strategic planning.

Feith supervised the Pentagon Office of Special Plans, and was responsible for the de-Ba'athification in Iraq, which was similar to the post-WW2 ‘De-Nazification’ of Germany.

Kolomoisky briefly served as governor of Ukraine’s Dnipropetrovsk region in 2014. He is said to have funded anti-Russian militia, including groups such as 'Azov Bataillon'. 1+1 Media aired the comedy series Servant of People featuring to-be President of Ukraine, Volodymyr Zelensky.

Lander announced his registration from the Biden administration effective February 18, 2022, after allegations spread that he had engaged in bullying and abusive conduct towards his subordinates and other White House Staff.

Prior to serving under President Biden, Klain served as chief of staff to Vice President Al Gore from 1995 to 1999, and for Biden as Vice President from 2009 to 2011. He also served as White House Ebola Response Coordinator under President Obama, and as a senior advisor to Biden's presidential campaign.

Cohen previously worked at the US Treasury Department, and as a privately practicing attorney. While serving as the Under Secretary for Terrorism and Financial Intelligence at the Treasury, he earned the nickname "sanctions guru".

Haines in the first woman to serve as the US Director of National Intelligence. She previously served as Deputy National Security Advisor, and Deputy Director of the Central Intelligence Agency in the Obama administration. She was the first woman to serve either of these roles.

Mayorkas was born in Havana, Cuba.

His family fled to Florida shortly after the Cuban Revolution, when Mayorkas was only one year old.

Garland previously served as a circuit judge of the US Court of Appeals for the DC Circuit from 1997 to 2021.

From 2011 to 2015 Sherman served under Hillary Clinton as Under Secretary of State for Political Affairs, the fourth-ranking official in the US Department of State. In this role, she was the lead negotiator for the 'Joint Comprehensive Plan of Action', better known as the Iran Nuclear Deal.

Blinken previously served as deputy national security advisor, and later deputy secretary of state under President Obama. He also served in the State Department and in senior positions on the National Security Council during the Clinton Administration.